Day Or Nightwhen Is The Best Time To Take Your Blood Pressure Medicine
ANKARA, TURKEY – NOVEMBER 14: A woman takes a pill on November 14, 2018 in Ankara, Turkey.
If you have high blood pressure, remembering to take your medication is so important.
In fact, the time of day when you take your medicine could influence your risk for complications such as heart attack and stroke, which is ultimately related to how well you manage your blood pressure.
The bodys natural rhythm, known as the circadian rhythm also affects how we respond to specific medications, the result of a complex interplay between your medication and cortisol, the chief hormone responsible for this rhythm.
Now, a new study recommends that you take your blood pressure medicine at bedtimeto lower your blood pressure during the night and early morninghelping to prevent elevation of blood pressure that normally occurs as you awaken.
The research was published earlier this week in the European Heart Journal.
There is a growing body of evidence which indicates that not only genetics, but the time of day you take a medicine may influence how effective it is for treating a particular condition.
The current study looking at this phenomenon represents the largest study to date of patients with high blood pressure, and included more than 19,000 persons on medications to treat high blood pressure.
The key here is routines, said Bhusri. An even routine has shown that patients are more compliant with taking their medications more regularly and not forgetting.
Taking Blood Pressure Pills At Bedtime Best For Cardiovascular Health
New research suggests that the best time for people with hypertension to take their blood pressure pills is at bedtime rather than in the morning.
It appears that not only does this timing result in better blood pressure control, but that it also markedly reduces the risk of cardiovascular death and events such as a heart attack or stroke.
Researchers came to these conclusions after analyzing data from the Hygia Chronotherapy Trial.
Hygia is the largest and longest lasting clinical trial to examine the effects of antihypertensive medication timing on the risk of cardiovascular events.
The investigators behind the present findings randomly assigned 19,084 adults to take the blood pressure pills that their doctors had prescribed either when they woke up in the morning or at bedtime. The participants were of Caucasian Spanish descent, and 8,470 were female.
During an average follow-up of 6 years, all individuals underwent 48-hour ambulatory blood pressure monitoring at least once per year.
The results of this study, says Ramón C. Hermida, Ph.D., the leader of the Hygia project, show that patients who routinely take their antihypertensive medication at bedtime, as opposed to when they wake up, have better-controlled blood pressure and, most importantly, a significantly decreased risk of death or illness from heart and blood vessel problems.
He and colleagues report the recent findings in the European Heart Journal.
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Why Is The Timing Of Your Medication Important
According to AARP, blood pressure follows a daily rhythm. It rises higher during the day and falls at night when we sleep.
Since morning blood pressure is usually highest, people often opt to take their medications then. Many also feel that it is easier to remember morning medications.
Also, since many medications cause urination, people may prefer to take them early in the day.
As we age, however, we may develop a blood pressure pattern called non-dipping. Non-dipping blood pressure tends to remain high overnight.
People ages 55 and older with high blood pressure are more prone to non-dipping.
Non-dipping blood pressure is a problem because it is a major risk factor for several conditions, including heart attack, stroke, and kidney disease.
Overnight blood pressure control is important in order to lower your risk.
If your medication wears off before your next dose is due, your blood pressure may be elevated for several hours while you sleep. You may also wake with high blood pressure.
Taking your medication at bedtime may help prevent this issue.
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When Is The Best Time To Take Your Blood Pressure Medication
Day or night – when is the best time to take your blood pressure medication?
A major study has revealed that taking blood pressure medication at bedtime rather than on waking halves the risk of events such as heart attack and stroke.
It’s a simple tip that could save lives, researchers of the study say in the European Heart Journal.
There is mounting evidence that many different drugs, including heart pills, might work better when taken at specific times of the day and experts believe our body’s biological ‘clock’ or natural 24-hour rhythm alters our response to the medication.
This latest trial is the largest so far to look at the phenomenon with high blood pressure pills, and included more than 19,000 people on these medications.
In the Spanish study:
- The patients were put into two groups at random – one group took the pills in the morning and the other group took them at bedtime
- Researchers monitored what happened to the patients over the next five or more years
- Patients who took their medication in the evening had nearly half the risk of dying from – or having – a heart attack, stroke or heart failure
The research suggests taking medication in the evening helps keep night-time blood pressure in check, in patients diagnosed with high blood pressure .
Lead researcher Prof Ramon Hermida, from the University of Vigo, said doctors might want to consider recommending it to patients: “It’s totally cost-free. It might save a lot of lives.
Why Does My Blood Pressure Vary Throughout The Day
You may have heard the term circadian rhythm. If so, you know this is not a beat to keep on the dance floor. It is a biological cycle your body follows. As defined by the National Institute of General Medical Sciences, âCircadian rhythms are physical, mental and behavioral changes that follow a roughly 24-hour cycle, responding primarily to light and darkness in an organism’s environment.â As your body cycles through this rhythm each day, responding to both internal and external stimuli, your blood pressure is affected.
The study of these important rhythms, known as chronobiology, was founded by Franz Halberg. His work in this field has helped identify abnormal rhythms in day-night blood pressure readings.Keeping the Beat of Blood PressureFollowing this chronobiological rhythm, your blood pressure is normally higher during the daytime and lower at night, during sleeping hours. Hereâs the problem. People with high blood pressure often donât experience this night time dip. This lack of a lowering of blood pressure at night is referred to as non-dipping.Whatâs the big deal? Heart attack and stroke have been found to be associated with non-dipping. Your blood pressure stays elevated, and your body is not in the relaxed state it should be during rest.
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Choosing Times That Work For You
The best times of day to take your blood pressure depend on you and your daily routine. Its important to pick times that you can stick to every day.
Taking your blood pressure at the same time each day is key to understanding your blood pressure. It can help make sure that the readings you take arent affected by the events of your day.
You can select times when you know youll be home and are unlikely to be interrupted. For example, you could check your blood pressure before you leave for work, when you get home from work, and before bed.
Taking These Medications At Bedtime Rather Than In The Morning May Make Them More Effective
Many people take their medications as part of their morning ritual, along with a cup of coffee and the daily newspaper. But for blood pressure drugs, evening may be a better option. Last year, a large study found that taking blood pressure drugs before bed may lower the risk of serious heart-related complications more than taking the drugs in the morning .
The concept of chronotherapy, or adjusting medication dosing to a specific time of day, isn’t new. There’s not a great deal of evidence to support the practice with cardiovascular drugs, but it makes sense, says Dr. Naomi Fisher, director of the Hypertension Specialty Clinic at Harvard-affiliated Brigham and Women’s Hospital.
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