Thursday, September 28, 2023

Mpv Blood Test High Symptoms

How To Correctly Read The Values Of A Vpm Exam

What are the symptoms of high MPV?

To understand the MPV value in a blood test You should look for the «VPM» indicator among the results of the tests you did in the laboratory.

Generally, both the MPV value and the platelet count per blood volume are included.

The normal platelet count in an adult is in the range of 150,000 to 400,000 per microliter of blood, and a normal mean platelet volume value should be in the range of 5 to 15 femtoliters .

A value below 5 or above 15 is cause for concern.

Compare your results to the normal range. Many laboratories display the normal reference range next to the test results.

Determine if your mean platelet volume value is high, possibly suggesting high blood pressure or other heart problems.

If not, it determines if the value is low. A low result may suggest more important health problems such as leukemia, human immunodeficiency virus, or bone marrow cancer.

Extremely low values in the mean platelet volume create a great risk for the patient of suffering coagulation problems in case of trauma, that is, suffering a significant loss of blood in any wound or injury.

Mpv And Rheumatic Diseases

A low MPV is usually related to inflammatory states. A recent study correlated MPV with inflammatory and disease indexes in rheumatic disorders. An inverse correlation of MPV with erythrocyte sedimentation rate , C-reactive protein , and DAS-28 was found in RA patients. MPV correlated negatively with both the BASDAI in ankylosing spondylitis and with CRP in psoriatic patients. An inverse correlation of MPV with ESR was also seen in lupus patients. Overall, a low MPV level surrogated inflammatory states in a large number of rheumatic patients. The authors suggested that MPV works as a negative marker in these patients .

There has been a recent interest in MPV levels in patients with SLE. A Mexican study accounted for lower MPV levels in active lupus patients as compared to those with inactive disease. At a cutoff level of 8.32 fL, MPV sensitivity and specificity for detecting active disease were 86 and 41%, respectively. Of note, a positive correlation of MPV with albumin levels was documented . Another group of authors reported lower MPV levels in patients with active lupus arthritis in comparison to SLE patients in remission or healthy controls .

Reports of MPV in psoriatic arthritis are sporadic. According to a 2010 study, MPV levels were higher in patients with psoriasis and psoriatic arthritis than controls. MPV may be a marker of severe psoriasis. Also, the authors suggested that increased platelet activation might associate with cardiovascular risk in these patients .

What Does It Mean If Your Mean Platelet Volume Result Is Too Low

A low MPV indicates that the average platelet size is small. Older platelets are generally smaller than younger ones therefore, a low MPV may mean that a condition is affecting the production of platelets in the bone marrow.

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How Is Aplastic Anemia Treated

Your treatment plan depends on several factors, such as your age, overall health and symptoms. Aplastic anemia treatment may include:

  • Immunosuppressants: These medicines suppress your immune system. Aplastic anemia symptoms improve in about 2 out of 3 people who take immunosuppressive medications.
  • Bone marrow stimulants: Certain types of drugs can stimulate your bone marrow to produce more blood cells. You may take sargramostim , filgrastim or epoetin alfa .
  • Blood transfusion: Transfusions replace red blood cells and platelets. Transfusions are not a cure for aplastic anemia, but they can treat symptoms like fatigue or bruising easily.
  • Supportive antibiotics depending on the severity of your blood counts.

Appendicitis Cause Mpv Levels To Drop


Low MPV blood test results can help diagnose acute appendicitis.

A study published in the Turkish Journal of Emergency Medicine reported that acute appendicitis can be difficult to diagnose. However, MPV levels were significantly lower than the mean values if the stomach pains were caused by inflammation of the appendix. This information can help doctors make an accurate diagnosis of appendicitis.13

Although your appendix is located on the right side of your lower abdomen, appendicitis pain usually starts as pain around your belly button.

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How Do Healthcare Providers Treat Thrombocytopenia

You might not need treatment if a low platelet count isnt causing significant issues. Often, healthcare providers can improve platelet counts by treating the underlying cause. This approach may involve changing your medications. Other treatments include:

  • Steroids: These medications may boost your platelet production.
  • Blood transfusion: If your platelet level is very low, your healthcare provider may use blood transfusions to temporarily increase your platelet levels. Transfusions may boost levels for about three days.
  • Splenectomy: This is surgery to remove your spleen. Your surgeon may do this if tests show your spleen is trapping large numbers of platelets. People who have splenectomies have an increased risk of developing infections. They may receive vaccinations to prevent infections.

How Is Thrombocytosis Diagnosed

As thrombocytosis doesnt typically cause symptoms, the first sign is often a high platelet count that shows up during routine blood work .

Thrombocytosis involves having more than 450,000 platelets per microliter of blood. If you have elevated levels, your healthcare provider will likely order a follow-up blood test a few weeks later to see if your levels remain high. Levels that are momentarily high but then return to normal arent usually concerning. Levels that remain elevated may signal an underlying condition.

Identifying the underlying condition thats raising your levels helps healthcare providers diagnose and manage reactive thrombocytosis. If your provider cant find a secondary cause, theyll run tests to see if you have essential thrombocythemia.

Tests may include:

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How Is A Blood Test Performed In The Lab

Depending on the symptoms you are experiencing, your doctor may order a MCV and MPV test. In most hospitals MCV and MPV results can be obtained within three to six hours after blood is taken. The blood is usually drawn from a vein on the inside of the elbow or the back of the hand. Drink plenty of water before your appointment. If you experience any symptoms that you are concerned about are out of the ordinary, call your doctor immediately.

Higher Risk Of Spontaneous Bleeding

How can I improve my MPV?

If the blood platelet count falls below , a person can begin bleeding spontaneously. This is a medical emergency, and people who experience spontaneous bleeding may require a blood, or platelet, transfusion.

Low platelet count increases the risk of death in people who experience a traumatic injury.

Several factors can cause a persons platelet levels to change. These include acute and chronic medical conditions and age.

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What Would A High Vpm Mean In My Exams

A is common in patients with certain forms of diabetes. Depending on other values detected in blood tests, they may indicate the presence of conditions such as .

In the thrombocytopeniathe persons immune system destroys the platelets.

It can also be a sign of a pregnancy complication that raises your blood pressure, called .

According to the values found, a high MPV could indicate a state of sepsis, or the bodys inflammatory response to an infection.

Another disease that alters and raises MPV values is , which causes an excess production of white blood cells.

Hyperthyroidism and bone marrow problems also cause excessive production of platelets.

What if my VPM exam values are low?

Various forms of anemia, as well as kidney failure problems, can lower platelet production.

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Some drug therapies that are toxic to blood cells also cause this type of condition. This is a common occurrence in cancer chemotherapy treatments.

WARNING: This article should not be taken as the equivalent of professional medical advice. Consult your trusted doctor if you have any questions about this or any other issue related to your health.

How Is Thrombocytopenia Treated

The treatment for thrombocytopenia depends on:

  • what’s causing it
  • how low the platelet count is
  • whether or not there is bleeding

Sometimes no treatment is needed and the thrombocytopenia clears up on its own. But some types need medical treatment to raise the platelet count to a safer level and to treat the underlying cause.

Thrombocytopenia is usually treated by a , a doctor who specializes in diagnosing and treating blood disorders.

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Low Mpv Blood Test Can Indicate Inflammatory Bowel Disease

One reason that your blood test results show low MPV is that you have an inflammatory condition of the digestive tract.

According to the American Journal of Gastroenterology, MPV is significantly reduced in people who have inflammatory bowel disease . It was found that inflammatory conditions like ulcerative colitis and Crohns disease caused the average size of platelets to be reduced. This gives doctors a way to help diagnose and monitor the activity of IBD.8

The journal Digestive Diseases and Sciences reported that treatment for IBD helps to increase MPV. When patients were treated with anti-inflammatory drugs for Crohns disease, there was a significant rise in MPV over a 14-week period.9

Inflammatory bowel disease is one reason why your digestive system doesnt work properly. It can cause abdominal muscle spasms, diarrhea after eating, and general discomfort in the abdominal area. According to doctors from the Mayo Clinic, doctors may also take a blood test for anemia and recommend vitamin B-12 shots to help prevent anemia and a vitamin B12 deficiency.

Signs Symptoms And Complications Of Thrombocythemia And Thrombocytosis

What Is The Mpv Blood Test

People who have thrombocythemia or thrombocytosis may not have signs or symptoms. These conditions might be discovered only after routine blood tests.

However, people who have primary thrombocythemia are more likely than those who have secondary thrombocytosis to have serious signs and symptoms.

The signs and symptoms of a high platelet count are linked to blood clots and bleeding. They include weakness, bleeding, headache, dizziness, chest pain, and tingling in the hands and feet.

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High Bun And Mpv Can Be Caused By Numerous Problems

High levels of BUN and MPV in the blood indicate a variety of health problems. If your blood BUN level is between 6 mg/dL to 20 mg/dL and the MPV level is between 6.8 mg/dL to 10.9 fL, then your body does not have any underlying health problems. But if BUN and MPV levels exceed these levels, you should see a doctor immediately.

How Do I Take Care Of Myself With Immune Thrombocytopenia

There are some things you can do that may lower your risk of bleeding. These include:

  • Avoiding sports that can put you at risk for injuries that could bleed.
  • Checking with your provider before you take any medicines or herbal supplements because they could make you more likely to bleed.
  • Protecting your body from injury by wearing gloves and using seat belts.

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Is There A Treatment That Cures Aplastic Anemia

A bone marrow transplant is the only cure for aplastic anemia. Bone marrow transplants are also called stem cell transplants. A transplant is the preferred treatment for severe aplastic anemia.

Bone marrow transplants replace damaged stem cells with healthy ones. The healthy stem cells may come from:

  • Donated bone marrow.
  • Peripheral stem cells .
  • Umbilical cord blood.

Normal Range Of Mpv : 68

MPV Blood Test | Mean Platelet Volume | Platelet Indices |

Ideal values of MPV depending on age :


*Ideal values are calculated based on our database of patient records

If you want your blood test report to be interpreted by MPV specialist, then you can upload your report. Our MPV expert will provide you with the most accurate interpretation of your blood test results and treatment within 12 hours. Upload blood test report now

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How Long Will You Have Immune Thrombocytopenia

Children with acute immune thrombocytopenia often get better without treatment in a few weeks or months and the problem doesnt come back. Some children need medicine or surgery.

Chronic immune thrombocytopenia can last for years, but you can live a long time even if your immune thrombocytopenia is severe. Most of the people who have chronic immune thrombocytopenia reach a point when they can stop getting treatment.

Consult A Doctor For Your Bun Problem

High BUN and MPV levels in the blood can cause a number of health problems. Your GP may recommend follow-up tests to get an important picture of your overall health and well-being. If the results are greater than 20 mg/dL for BUN and more than 10.9 fL for MPV, you may also need some follow-up tests that will help detect the underlying disease early.

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Q5 How Do I Lower My Mpv

There are many ways to lower MPV and this includes:1. Eating the right foods such as vegetables, fruits, whole grains, and low saturated fat foods.2. Exercise regularly. Spend at least 30 minutes a day doing moderate physical activities.3. Avoid vices such as smoking and drinking.4. Maintain a healthy weight.

Higher Risk Of Blood Clots

MPV Blood Test Information and How Mean Platelet Volume Levels Can Help ...

A persons blood clots more quickly when they have too many platelets.

Clotting is a natural protection against bleeding. The body produces more platelets during and following an injury.

However, because platelets cause blood clotting, they can also cause dangerous blood clots in the arms or legs. The blood clot may break off or travel to another area of the body.

The risk of a blood clot is higher in people confined to bed by illness or who cannot move their limbs.

Someone who has a high platelet count because of a recent injury but who must remain in bed may need monitoring to reduce the risk of blood clots as a result.

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What Are The Risks Of Having An Mpv Blood Test

There are minimal risks to having an MPV blood test, besides a small pinch when the lab technician inserts the needle and a mild amount of bleeding. If you have excessive bleeding or develop a large bruise on your arm, let your doctor know right away. These symptoms may indicate a bleeding disorder.

What Does A Platelet Count Test

A healthy platelet count is between 150,000 to 450,000 platelets per microliter of blood. If your platelet count is within that range, that may show that you have an average amount of platelets. However, if it falls under 150,000 or above 450,000, that could suggest that you have a health problem. Thrombocytopenia and thrombocytosis are two possible conditions that a low or high platelet count could be a sign of.


If your platelet test shows that you have a platelet count of under 150,000 per microliter of blood, that means you have thrombocytopenia. Thrombocytopenia means that your body has trouble making enough blood clots to help you guard against injury or impact. People with thrombocytopenia find themselves bruising or bleeding quite easily.

It is usually caused by:


Thrombocytosis is when the mean number of your platelets within your blood is higher than average. There are two types of thrombocytosis: primary and secondary.

Primary thrombocytosis is when abnormal cells get into bone marrow and increase the production of platelets. This condition is relatively mysterious, and its causes are not known.

Secondary thrombocytosis is medically the same as primary thrombocytosis but is caused by some other condition or disease. It can be caused by cancer, inflammation, infection, bone marrow disease, or anemia . Typically, secondary thrombocytosis is treated by treating whatever is causing it.

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What Is A Normal Mean Platelet Volume

The normal value for the MPV is variable because it depends on the exact instrument employed to measure it. In adults, a normal MPV is usually considered to be around 7 to 13 femtolitres however, you should look for the reference range that your laboratory reports. A full blood count test taken with Vitall always includes the appropriate range for your age and gender.

A normal MPV says a lot about platelet function and production. Most of the platelets have a normal size, which frequently means that there is a good response to bleeding and adequate clot formation. Usually, the MPV is inversely proportional to the platelet count in other words, when platelets are too big, they tend to be fewer in number. However, this balance can be altered by some diseases. For correct interpretation, the MPV should be evaluated alongside the platelet count.

Up to five per cent of platelets are naturally larger than average these are young, recently produced platelets that will become smaller after a couple of days. Considering they are a small portion of the total count, they do not influence the MPV.

What Can I Expect If I Have This Condition

Can anemia cause high MPV?

Many things can cause your platelet levels to drop so you develop thrombocytopenia. For example, you may have an autoimmune disease that affects your platelet levels. You may have low platelet levels because you drink lots of alcohol or are exposed to certain toxic chemicals.

Bottom line once your healthcare provider finds out why your platelet levels are low, theyll take steps to help you. If you have thrombocytopenia, ask your healthcare provider what caused the issue and what treatment or lifestyle changes they recommend.

If your provider recommends treatment, you may need ongoing treatment to maintain a normal platelet level. Your provider will monitor your overall health and platelet levels.

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