Can Prednisone Raise Blood Pressure
Yes, one of the possible side effects of prednisone is elevated blood pressure. The increase in blood pressure occurs due to two reasons – fluid retention and weight gain.
Prednisone affects certain receptors on the kidneys, leading to sodium and water retention. When the body retains excessive sodium and fluid, it increases the total volume of blood, leading to high blood pressure.
Another way in which prednisone can increase blood pressure is through weight gain. Prednisone mimics the natural hormone cortisol made by the adrenal glands in the body cortisol is known to affect metabolism and appetite. Similarly, prednisone causes increased appetite, which leads to excess calorie intake and weight gain. People who are overweight or obese have a considerably higher risk of developing high blood pressure. Conversely, healthy weight loss can help control blood pressure.
Other side effects of prednisone besides fluid accumulation and weight gain include elevated blood sugar, sleep problems, skin thinning, mood swings, bone loss, suppression of the immune system, weakness, tiredness, and heartburn, among others.
When Should You See A Doctor
Early high blood pressure detection is essential. This silent killer often shows no warning signs and therefore puts people at a higher risk of conditions such as:
Over 360,000 high-blood-pressure deaths occurred in 2016 in the US, whether hypertension was a contributing cause or the main cause.¹²
The only way to identify if you have high blood pressure is to measure it. You can visit your healthcare provider for regular blood pressure monitoring, or you can purchase a sphygmomanometer to measure your blood pressure at home.
If you’re at risk of high blood pressure, you need to schedule routine healthcare visits to monitor your blood pressure. You should also see your healthcare provider if you have high blood pressure and your efforts to reduce your blood pressure have been ineffective.
Handling Prednisones Side Effects Naturally
In order for patients with pemphigus and pemphigoid to get control of their disease, there are certain drugs that patients must take. Prednisone is the first drug of choice for treating these diseases. Immunosuppressive drugs are often given as well to help patients reduce the doses of corticosteroids .
Prednisone is one of the most successfully and one of the most commonly used drug for treating a variety of diseases, but it can have many side effects. Some of the effects of long-term steroid use on our health are: weight gain, increased appetite, loss of muscle mass and bone density, increased fatty deposits, reduction in zinc, Vitamin D, and C levels loss of potassium, fluid retention, gastric problems, hypertension, high cholesterol, and hampering the bodys ability to handle blood sugars.
An important fact to remember, however, is that although there are many problems and side effects that can occur when using steroids , not everyone will experience the same ones. As significant as these side effects can be, there are things we can all do nutritionally that might help lower these effects.
Although many of these side effects can be controlled with medication, there are many good foods that might help reduce the devastating effects of steroids.
Weight bearing exercises are helpful in keeping bones healthy.
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Preventing High Blood Pressure
If you are already taking blood pressure medications when you began taking prednisone, your healthcare provider may adjust these medications. They may just recommend monitoring your blood pressure to assess how your body is responding to prednisone.
If you develop high blood pressure while taking prednisone, your healthcare provider may recommend starting blood pressure medication to help.
Lifestyle changes can be implemented to help prevent high blood pressure. Eating a balanced diet of fruits, vegetables, whole grains, and healthy fats can help with maintaining a health weight.
It also helps to limit the total amount of salt in your diet. It is recommended to limit your salt intake 2 grams or 2000 milligrams sodium per day. This includes the sodium that naturally occurs in food, salt added during processing, and any salt you add to your foods.
Try these tips to help reduce your overall salt intake:
- Keep saltshakers off of the table and avoid adding salt after you’re done cooking.
- Cook with other herbs and spices that don’t have salt added to them, such as black pepper, oregano, cumin, onion powder, garlic powder, and any spice blend without sodium.
- When purchasing canned or processed foods, choose those labeled low sodium or no salt added.
- Read the label to see how many milligrams of sodium it has per serving and the serving size.
- Rinse can foods to help remove a lot of the extra salt that is added during processes to help preserve the food.
Prednisone Side Effects In Women And Men

Because corticosteroids, such as prednisone, impact hormones, they can affect men and women differently. Women are more likely to develop osteoporosis, a serious side effect from prednisone use. And women who are pregnant, who want to get pregnant or who are breastfeeding should not take prednisone.
For men, prednisone can cause erectile dysfunction and change testosterone levels. Some men reported reduced sperm counts and infertility.
Men and women experience similar side effects, including depression, mood swings and stomach pain. But overall, doctors need more research to understand the specific role of gender in reactions to corticosteroids.
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Definition Of Oral Glucocorticoid Exposure
We defined glucocorticoid exposure status using all drug prescriptions for oral glucocorticoids issued in primary care. We extracted glucocorticoid doses from the directions given , product strength and prescribed quantity. We converted dosages into prednisolone-equivalent dose to account for differences in potency of different types of glucocorticoids.19 See Appendix 1, Supplementary Table 3 for conversion rates.
To prevent length- and time-dependent bias,20 we analyzed periods covered or not by medication prescription .
We constructed time-variant continuous and categorical variables of daily dose and cumulative dose . The categories for daily dose were nonuse, > 04.9, 5.07.4 and 7.5 mg and for cumulative dose were nonuse, > 0959.9, 9603, 054.9, and 3055 mg. We based cut-offs for the categorical variables on previous studies2123 to facilitate comparability.
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How Long Does It Take For Prednisone To Leave Your Body
Prednisone leaves your system in between 16.5 and 22 hours. Prednisone has a half-life of around 3 to 4 hours, depending on dosage. Your body needs this amount of time to cut plasma levels in half. Half-life of a medication is about 5.5 times the time required for its full excretion from a human body.
Causes Of High Diastolic Blood Pressure And What You Can Do To Lower It
Your blood pressure is a measure of the pressure of your blood pushing against your artery walls as your heart pumps it around your body. High blood pressure, also known as hypertension, is a condition where blood flows through your arteries at a pressure that is higher than usual. Normal blood pressure is less than 120/80mm Hg.¹
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Mental Health Side Effects

Early in treatment , prednisone may increase feelings of well-being, anxiety, hypomania or mild euphoria. With long-term therapy, however, people may develop depression. Psychosis, referred to as corticosteroid-induced psychosis, can occur at doses of 20 mg or more per day with long-term use.
Mental health issues start within 3 to 4 days after starting prednisone therapy, but they can occur at any time. Some people continue to have symptoms, including depression, even after therapy stops.
Children who get prednisone for acute lymphoblastic leukemia , may develop mood fluctuations, depression, manic behavior or euphoria. For most, symptoms go away when therapy concludes.
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Do Steroids Cause Heartburn
Yes, steroid use can cause heartburn due to the fact that they increase levels of stomach acid.
This is because steroids suppress the natural production of cortisol, which is a hormone that helps to keep stomach acid levels in check.
When levels of stomach acid increase, it can cause that burning sensation in your chest known as heartburn.
If youre experiencing heartburn while taking steroids, there are a few things you can do to help relieve the symptoms.
First, try eating smaller meals more often throughout the day, rather than three large meals.
Its also a good idea to avoid spicy foods or anything that may trigger your heartburn .
Finally, if these changes dont help with the problem then you should talk to your doctor about switching steroid medications since not all of them have this side effect.
Do Steroids Cause High Blood Pressure
Yes, long-term steroid use can lead to high blood pressure due to the fact that they increase levels of a hormone called renin.
Renin is produced by the kidneys and helps to regulate blood pressure by controlling the production of angiotensin II, which is a hormone that causes the blood vessels to tighten.
When renin levels increase, it can lead to an increase in blood pressure.
If youre taking steroids and experience high blood pressure, its important to see your doctor right away. High blood pressure can cause a number of health problems if left untreated.
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How Long Does It Take Blood Pressure To Go Down After Steroids
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Rutgers Study Is The First To Quantify These Complications Of Oral Steroids In A Nationwide Population Of Children
Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.
The study, which was published in the American Journal of Epidemiology, examined the records of more than 933,000 US children from ages 1 to 18 with or without autoimmune diseases, such as inflammatory bowel disease, juvenile arthritis or psoriasis. Among those without an autoimmune disease, about two in three children who received prescriptions for steroids had evidence of asthma.
The rates of diabetes, high blood pressure and blood clots from oral steroids have been studied in large populations of adults. However, there are reasons to think these findings might be different in children, who not only tend to take steroids differently than adults but also have much lower baseline risks of developing these same cardiovascular and metabolic conditions. This study allowed us to put numbers on the association between oral steroids and rare, but potentially serious, complications in children, said study author Daniel Horton, an assistant professor of pediatrics and epidemiology at Rutgers Robert Wood Johnson Medical School.