How Can I Minimize My Risk For Heart Disease
Diet, regular exercise, and blood pressure and cholesterol control all help reduce the risk. For those with diabetes, its important to closely monitor blood sugar. Also, consider talking to your doctor about starting an aspirin regimen or taking hydroxychloroquine , which has been shown to be cardioprotective by lowering total cholesterol and blood glucose levels. Finally, because smoking causes a threefold higher risk of a heart attack when you have lupus, consider quitting.
Can Someone With Lupus Take Statins For Cholesterol
Statins are the preferred treatment for high cholesterol and heart conditions. Theyre often prescribed for people with lupus who have high cholesterol, or who are at risk for high cholesterol.
Recently, research has suggested that this standard approach might not be appropriate. A 2019 study found that statins were ineffective as a stand-alone cholesterol treatment for people with lupus. This appears to primarily be because the causes of high cholesterol are different in people with lupus than in people without lupus.
However, the results suggested that statins could be used alongside other cholesterol treatment options to help bring down cholesterol levels.
Currently, many people with lupus still take statins as part of an overall cholesterol treatment plan. Your doctor will likely also suggest other treatments, such as lifestyle changes, that can help manage your cholesterol. Youll have frequent cholesterol testing while you take statins to ensure that theyre helping you and to monitor your overall progress.
How Common Is Heart Disease In The United States
Heart disease is the #1 cause of death in Americans. In general, heart disease is more common in men than in women before the age of 55. Premenopausal women have lower risks of heart disease. Over the age of 55, men and women have equal risks of heart disease. Heart disease is more common in black women than in white women and it often is a more serious problem. Heart disease is the #1 cause of death in women of color.
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What Does Blood Pressure Readings Mean
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What Are The Risk Factors For Cvd In Those With Lupus

Traditional risk factors are high cholesterol, high blood pressure, obesity, smoking, sedentary lifestyle, and diabetes. Lupus-specific risk factors for heart disease are older age at diagnosis, longer disease duration, and longer periods of steroid use. More active lupus, a history of kidney disease, the use of non-steroidal anti-inflammatory drugs , and long-term use of corticosteroids also increase risk.
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Blood Pressure Meds Copd Asthma Problems
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Lupus And Heart Health Faq
Did you know people with lupus are at higher risk for heart problems, such as heart attacks and cardiovascular disease ? Risk factors for heart problems include high cholesterol and high blood pressure . Learn more about what the research shows about the connection between lupus-related inflammation and the heart.
Thankfully, there are things you can do to reduce your risk.
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How Does Lupus Affect White Blood Cells
White blood cells are actually made up of several different types of cells, including neutrophils , lymphocytes and monocytes. White blood cells are the bodys main defense against infection. A reduction in the number of white blood cells is called leukopenia a particular reduction in granulocytes is called neutropenia .
Leukopenia and neutropenia are very common in active lupus, but rarely are white cell counts low enough to lead to infection. Counts may be lowered by azathioprine, cyclophosphamide and some other drugs. Therefore, white cell counts are always monitored during treatment with these agents. If counts go too low, the prescribed drug is usually stopped briefly or the dosage is reduced. When infections occur in lupus, they are more often related to alterations in the bodyâs immune system that are not reflected in routine blood counts.
What To Expect When You Take Blood Pressure Drugs
Before you begin any medications, tell your doctor about all drugs, vitamins, and supplements that youâre on. You should be aware of any side effects and if there are any dangerous interactions with each type of drug.
Diuretics. The common side effects of these drugs, depending on which one you are on, are muscle cramps, weakness, rash, sensitivity to sunlight, cramps, vomiting, diarrhea, lightheadedness, or pain in your joints. You might also notice less common side effects like erectile dysfunction or an irregular heartbeat.
These symptoms can be similar to the side effects from lupus. If you notice new side effects, talk to your doctor. Itâs important that you donât stop these medications unless your health care team suggests you do so. Many of these drugs could affect your kidney function. If you stop them without your doctorâs approval, it could cause problems.
Be careful of interactions with drugs such as digitalis and digoxin and certain antidepressants.
ACE inhibitors. Some of these drugs can make the amount of lithium in your blood go up, which could lead to side effects.
Other possible side effects include a cough, higher blood potassium levels, low blood pressure, constipation, dizziness, headache, sleepiness, weakness, a metallic or salty taste, or a rash. Less common ones could include kidney failure, allergic reactions, a lower white blood cell count, and angioedema .
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Hypertension And/or High Cholesterol
About half of all lupus patients have high blood pressure, which forces your heart to work harder, contributes to hardening of the arteries , and raises the risk of stroke. Many people with lupus also have too much LDL (bad cholesterol as well as triglycerides, both of which can clog arteries.
Meanwhile, HDL cholesterol the kind thats typically described as good might not act the way that it should: Some lupus patients have dysfunctional HDL, which causes more inflammation and further contributes to the buildup of fatty plaque in the arteries.
What Time Of Day Best To Take High Blood Pressure Medicine
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Symptoms Can Be Readily Confused With Minor Issues
The symptoms an individual becomes likely to relate to multiple aspects which include genetics, environment, and personal well-being.
They can include swollen and painful joints but they do not become deformed.
Occasionally, the disease might occur in more than 1 member of precisely the same family.
If youre suffering from an autoimmune disease, then its most effective to discuss pregnancy and conception chances with your physician before you start trying for a baby.
Not all treatments are ideal for everybody, and the choice to treat is based on several factors, taking into consideration the entire patient.
It depends on the disease, but in most cases, one important goal is to reduce inflammation.
It also varies depending on the type of disorder.
Also, maintain a checklist of your symptoms so that you can monitor how youre feeling.
The most frequent symptoms have a tendency to be nonspecific, meaning they could result from a condition that doesnt have anything to do with the immune system.
Many autoimmune disease symptoms come and go and they are able to influence unique portions of the body.
Take Your Medications As Prescribed

As with other inflammatory conditions, high disease activity in lupus often correlates with a higher risk of cardiovascular disease. Working closely with your doctor and taking your medications as directed should help.
There is reason to believe that medications, such as hydroxychloroquine, methotrexate, or mycophenolate mofetil, each of which are used for different presentations of lupus, can decrease heart risk by decreasing inflammation in the system, says Dr. Fields.
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Why Does Lupus Cause Weight Gain Or Weight Loss
Many people with lupus may experience weight loss. This can be caused by the medications that are used to treat lupus or from the discomfort of the disease itself. On the flip side, some people may gain weight if they find that they are inactive due to joint pain. Its important to maintain a healthy diet when you have lupus. Talk to your healthcare provider and possibly a nutritionist to determine the best diet for you.
Risk Factors For Autoimmune Disease And Hypertension
Both SLE and hypertension are multifactorial diseases. Therefore, it may not be surprising that there is overlap among genetic and environmental risk factors for the development of autoimmune diseases and hypertension. For example, smoking and body mass index associated with poor outcomes for patients with SLE and with the risk of developing hypertension . However, patients with SLE have an increased risk for CVD mortality beyond traditional risk factors, suggesting that disease-specific factors play an important role . Below, some of the SLE-specific risk factors, which contribute to SLE susceptibility and likely contribute to the increased prevalence of hypertension, are discussed.
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Eating Healthy And Staying Active
It’s important for people with SLE to maintain a healthy diet, especially if the disease has caused problems with high blood pressure, cholesterol, kidney function, or other complications. Discuss with your doctor if you need to make any dietary changes based on your specific health profile. Ask your doctor whether you should take a vitamin D supplement — many people with lupus have low levels of vitamin D because they need to avoid exposure to sunlight.
People with SLE should try to maintain a healthy and active lifestyle. Light-to-moderate exercise, interspersed with rest periods, is good for the heart, helps fight depression and fatigue, and can help keep joints flexible.
Subject Characteristics And Selected Metabolic Risk Factors
There were no differences in age, male/female ratio, anthropometric measures, blood lipids, or blood glucose among the three groups . The difference between sedentary SLE and other groups were not significant . Sedentary SLE and physically active SLE had similar disease duration , patient global assessment score , corticosteroid use , hydroxychloroquine use , and serum anti-double-stranded DNA concentrations . carotid intima-media thickness was similar between the three patient groups . Dietary intake of vitamins and sodium obtained with a 3-day dietary records were not different between the groups .
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Do These Treatments Have Side Effects
You should always speak with your doctor about the risks and benefits of any of the treatments you receive. Each of the drugs during any of these treatments can have their own side effects. Fortunately, these side effects usually are manageable for most patients. Discuss your treatment with your healthcare provider. Your overall health and the health of your kidneys should always be considered. There are times when the side effects of certain treatments are not worth the risk to your health.
If you are a woman with lupus nephritis and want to have children, you should discuss with your healthcare provider the effect your treatment may have on that process. There are ways to make sure that treatment is less harmful to this process.
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Cardiovascular Disease And Lupus
Systemic lupus erythematosus can affect your heart in a variety of ways some are life-threatening and others are much less serious. There are several risk factors for heart-related conditions, many of which can be avoided. It is important that you report any chest pain to your doctor so that together you can determine the cause and, when needed, develop an action plan to lower your risk of developing serious complications.
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What Is The Cause Of Hypertension In An Inflammatory State
Figure 1 depicts these mechanisms and the influence they have on inflammation in hypertension. Activation of dendritic cells and subsequent activation of T-cells are hallmarks of hypertension-induced immune activation. T-cells then spread to the vascular system and the kidney, resulting in hypertension and inflammation.
Lifestyle Changes Due To The Pandemic

The pandemic has caused people to undergo many lifestyle changes. Some of these can also cause high blood pressure. These changes include excessive weight gain and lack of physical exercise.
Weight gain due to the pandemic can be linked to the following:
- The bodys response to stress: When a person feels threatened or anxious, the body releases cortisol. This increases appetite and slows metabolism, leading to weight gain.
- A lack of exercise: During quarantine, people may stay indoors for long periods. This slows down the bodys metabolism, and the body begins to burn fewer calories. Exercise is linked to lower blood pressure.
During the pandemic, some people may have started or increased their use of nicotine and alcohol products, which can also raise blood pressure.
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How Does Blood Pressure Effect The Body
According to AHA, High bloodpressure damages the arteries that can become blocked and prevent blood flow to the heart muscle. Also the increased workload from high bloodpressure can cause the heart to enlarge and fail to supply blood to the body.
Does high blood pressure cause skin rashHigh blood pressure often does not cause symptoms, but regular screening can help a person know if they need to take preventive action. . skin rash swollen abdomen, in rare cases
Does Lupus Impact Cholesterol Levels
Lupus is an autoimmune condition. It occurs when your bodys immune system mistakenly attacks its own tissues, bones, and organs. Lupus can affect the whole body, including skin, blood cells, joints, brain, and heart.
When lupus affects heart health, it can affect blood pressure and cholesterol levels and can raise your risk for heart attack and stroke.
People with lupus are at a higher risk for high cholesterol. Theyre also at a higher risk for complications of high cholesterol than people without lupus.
This is an effect of inflammation. The constant inflammation of lupus causes stress and damage to the blood vessels, which leads to a faster buildup of plaque on the walls of blood vessels. This makes it harder for blood to travel through your body and can lead to a wide range of heart health complications.
Inflammation also affects how the body processes fats. It can slow down your metabolism and cause your body to store more fats. This can lead to increased cholesterol, especially bad, or LDL cholesterol.
Common lupus treatments, such as steroids, are known to raise cholesterol levels when taken in high doses. Additionally, the fatigue of lupus can lead to a sedentary lifestyle, and a lack of exercise is proven to raise overall cholesterol, raise levels of bad cholesterol, and limit levels of good, or HDL cholesterol.
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