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Is There Still A Role For Combination Therapy
Since the coadministration of tadalafil and -adrenergic antagonists is safe when following the proper instructions, another question that arises is the possible role of combination treatment in patients with BPH-associated LUTS, especially using the new more uroselective -adrenergic antagonists.
Recently, data on the combination of tadalafil with finasteride have been published . This study was an international, randomized, double-blind, parallel study including men with prostate volumes 30 ml or greater. The combination of tadalafil 5 mg and finasteride 5 mg improved IPSS significantly compared with finasteride monotherapy at all time points . IPSS improved by 1.7, 1.4 and 1 more in the combination group compared with the finasteride-only group at the above time points, respectively. As expected, IIEF improved significantly in the combination group . Combination therapy was well tolerated and most adverse events were mild/moderate. Interestingly, almost no sexual adverse event has been reported in the combination group.
While these preliminary data show that combination therapy may provide additional efficacy benefits, it is questionable whether these benefits are of clinical importance. In addition to significantly increasing the treatment cost, new data are required and combination therapy currently should be considered only in clinical trials.
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Will I Need To Use This Drug Long Term
If youre using Cialis to treat BPH, this medication may be a long-term treatment. Cialis may also be used to treat ED long term.
But in some cases, your doctor may determine the cause of your ED, such as depression or an illness. In such instances, you may be able to stop taking Cialis after the cause of your ED has been treated.
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What Is Cialis Side Effects Usage Dosage & More
Cialis is a prescription, brand-name medication approved by the Food and Drug Administration to treat symptoms of erectile dysfunction and benign prostatic hyperplasia .
Cialis is a safe and effective option for most men affected by one of these conditions. Cialis can also be used to treat symptoms of ED and BPH together. Because Cialis is only available by prescription, its important to talk to a healthcare professional to determine if Cialis is right for you.
To help you prepare for that conversation, this article describes who can take Cialis, how to take it, and how long it lasts, as well as its side effects, drug interactions, alternatives, and cost.
More Common Side Effects Of Cialis
Cialis can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days or weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.
These are just a few of the more common side effects reported by people who took Cialis in clinical trials:
These side effects may be temporary, lasting a few days or weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.
Note: After the Food and Drug Administration approves a drug, it tracks side effects of the medication. If you develop a side effect while taking Cialis and want to tell the FDA about it, visit MedWatch.
* For more information about this side effect, see Side effect specifics below.
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Alcohol And Food Interactions
Here are some other considerations to make before taking Cialis:
- Alcohol:Consuming large quantities of alcohol while taking Cialis can cause effects such as dilated blood vessels, dizziness, headache, fast heartbeat, and low blood pressure. Talk with your healthcare provider about your regular alcohol consumption before starting Cialis.
- Grapefruit:Eating grapefruit or drinking grapefruit juice can increase the levels of Cialis in your blood, raising your risk for side effects.
Can I Take Erectile Dysfunction Medication If I Have High Blood Pressure
Thanks to television, commercials, and other media, you may already be familiar with the correlation between erectile dysfunction and cardiovascular disease. Because of this, many men have questions about whether they can safely take ED medication with an underlying condition, such as high blood pressure. When starting any new prescription, including medications for ED, it is important to discuss it with your doctor.
The expert team at Kasraeian Urology, including renowned board-certified urologists Drs. Ahmad and Ali Kasraeian, provides advanced solutions for ED in Jacksonville, FL to help men regain a more enjoyable, reliable, and fulfilling sex life. Learn more about ED and hypertension here, including what treatment options you may have that are both safe and effective.
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Can Women Take Cialis
Cialis is not FDA-approved for the use in women. However, women with a low sex drive have other medication options, including the injectable bremelanotide and the pill flibanserin .
Women with pulmonary arterial hypertension can take Adcirca, which has the same active ingredient as Cialis, tadalafil. However, women with PAH should not take Cialis.
Does Running Help Lower Blood Pressure
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Is Cialis Good For High Blood Pressure
Cialis can lower blood pressure, which in principle, can be good for those with uncontrolled high blood pressure. However, it does not lower blood pressure to the extent that antihypertensives do, so it is unlikely to have a meaningful impact on lower blood pressure. If you have uncontrolled high blood pressure, you should not use Cialis. Lowering blood pressure and allowing it to increase above the normal range can put you at risk of having a heart attack.
Whilst all of our content is written and reviewed by healthcare professionals, it is not intended to be substituted for or used as medical advice. If you have any questions or concerns about your health, please speak to your doctor.
How Long Do Cialis Side Effects Last
Most common side effects of Cialis are temporary and will abate within a few hours or days after discontinuing the medicine. Some, like headache, back pain, and muscle pain were the main reasons a small number of people in the initial clinical trials stopped using Cialis.
Other side effects, such as severe allergic reactions, prolonged erections, priapism, hearing loss, and cardiovascular events require immediate medical attention and may require long-term attention. Severe but rare possible adverse events such as damage to erectile tissues due to priapism, hearing loss, heart attack, or stroke may have lifelong consequences. Vision loss due to NAION can be permanent.
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How Antipsychotics Affect Blood Pressure Medication
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Pregnancy And Breastfeeding While Taking Cialis
Cialis isnt approved for use in females.* Its not known whether the drug is safe to use while pregnant or breastfeeding.
If you have questions about Cialis and pregnancy or breastfeeding, talk with your doctor.
* Sex and gender exist on spectrums. Use of the term female in this article refers to sex assigned at birth.
Side Effects That Affect The Eyes And Vision
Although rare, taking Cialis can cause side effects that affect the eyes and vision. These side effects werent common in clinical trials, though.
Specifically, sudden vision loss in one or both eyes is a rare side effect of Cialis. This is because phosphodiesterase 5 inhibitors, such as Cialis, can cause non-arteritic anterior ischemic optic neuropathy . With NAION, blood flow to your optic nerve is cut off. Your optic nerve sends information from your eyes to your brain.
Other rare side effects reported in clinical trials of Cialis include:
- changes in color vision
- making more tears than usual
What you can do
Immediately stop taking Cialis and get emergency medical help if you have sudden loss of vision in one or both eyes.
If you have any eye problems, or if youve been told that you have a crowded optic disc, make sure your doctor knows this before you start Cialis treatment. People with a crowded optic disc may be at increased risk for NAION.
If you have symptoms of eye side effects other than vision loss, contact your doctor right away. Theyll likely want to see you to evaluate your symptoms.
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Changes In The International Index Of Erectile Function Score And International Prostate Symptom Score
The IIEF-5 and IPSS scores at baseline did not differ between the groups . However, improvement in the IIEF-5 score was significantly greater in the tadalafil group than in the placebo group at 3 months and 6 months . Moreover, we noted a numerical reduction in the IPSS of the tadalafil group however, the difference was not statistically significant when compared with the placebo group.
Surgery Surgery Is Used To Treat Bph When Drug Therapy Stops Workingor To Treat Those Who Cant Urinate At All It Can Also Be Used To Relievesevere Symptoms
Transurethral resection of the prostate
Transurethral resection of the prostate removesprostate tissue through the urethra. It is the surgery most commonly used totreat BPH. While TURP relieves urinary symptoms in most men, urinary problemscan come back over time if the prostate starts to grow again. This is why youngermen may need to have this surgery more than once.
This surgery is done in an operating room. The doctor passes a resectoscope through the urethra to reach the prostate. A resectoscope is a type of endoscope . It has a thin wire that carries an electric current. The doctor uses the electric current to cut away prostate tissue around the urethra. The doctor then removes this tissue through the resectoscope.
The most common side effects of TURP include:
In rare cases, you may develop erectile dysfunction orincontinence after TURP. But this surgery has a lower risk of these sideeffects than surgery to remove the prostate .
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Does Cialis Lower Blood Pressure
Medically reviewed by Katelyn Hagerty, FNP
Cialis®, known in its generic form as tadalafil, is one of the most commonly prescribed erectile dysfunction medications on the market today.
While other erectile dysfunction drugs such as Viagra® and Levitra® are taken as needed immediately before sex, tadalafils long half-life the amount of time it takes to eliminate 50 percent of the drug from your system renders it effective for up to 36 hours.
Tadalafil can also be taken at a low dose on a daily basis, which allows those on the medication to be ready for sexual encounters as they come up organically, rather than having to take a pill and wait for it to kick in.
But like any other medication, tadalafil can have side effects and may not be right for everybody particularly those with certain medical conditions or those taking certain medications.
Below, well talk about how Tadalafil works and the impact it can have on blood pressure.
Tadalafil belongs to a class of medications known as phosphodiesterase type 5 inhibitors, or PDE5 inhibitors.
PDE5 inhibitors are so named because they block an enzyme called cGMP-specific phosphodiesterase type 5 that breaks down cyclic guanosine monophosphate , a molecule that relaxes smooth muscles.