Sensors Of Blood Carbon Dioxide Concentrations
The pH of cerebrospinal fluid is very closely controlled by two mechanisms: respiration, and the adjustment of the blood flow to the brain. A downward shift of 0.05 pH units from the normal 7.32 of cerebrospinal fluid results in a ten-fold increase in ventilation and almost a doubling of cerebral blood flow. However, it is with the respiratory changes that this section is concerned.
Figure 17.4. The peripheral chemoreceptors. Gross appearance of a carotid body section through part of a carotid body.
George A. Vogler, in, 2006
What Are The Normal Co2 Levels
The normal levels of CO2 in your blood may depend upon various factors such as sex, age, and medical history. Sometimes, the normal levels of CO2 may also depend upon the range set by a certain laboratory, how the test is administered, and the kind of medication an individual is taking.
The normal range for CO2 in your blood is 23 to 29 mEq/L. According to age, the normal CO2 level of an individual aging 18 to 59 years old is from 23 to 29 mEq/L. For 60 to 89 years old, it is from 23 to 31 mEq/L. And for 90 years and above, it is from 20 to 29 mEq/L. According to sex, men usually have one mEq/L higher than women.
Normal Co2 Levels For Adults By Age
Age Group |
What Is Being Tested
Bicarbonate is an electrolyte, a negatively charged ion that is used by the body to help maintain the bodys acid-base balance. It also works with the other electrolytes to maintain electrical neutrality at the cellular level. This test measures the total amount of carbon dioxide in the blood, which occurs mostly in the form of bicarbonate . The CO2 is mainly a by-product of various metabolic processes.
Measuring bicarbonate as part of an electrolyte or metabolic panel may help diagnose an electrolyte imbalance or acidosis or alkalosis. Acidosis and alkalosis describe the abnormal conditions that result from an imbalance in the pH of the blood caused by an excess of acid or alkali . This imbalance is typically caused by some underlying condition or disease.
The lungs and kidneys are the major organs involved in regulating blood pH through the removal of excess bicarbonate.
- The lungs flush acid out of the body by exhaling CO2. Raising and lowering the respiratory rate alters the amount of CO2 that is breathed out, and this can affect blood pH within minutes.
- The kidneys eliminate acids in the urine and they regulate the concentration of bicarbonate in blood. Acid-base changes due to increases or decreases in HCO3 concentration occur more slowly than changes in CO2, taking hours or days.
Any disease or condition that affects the lungs, kidneys, metabolism, or breathing has the potential to cause acidosis or alkalosis.
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How Should We Prepare For A Cmp
Your child may be asked to stop eating and drinking for 8 to 12 hours before a CMP. Tell your doctor about any medicines your child takes because some drugs might affect the test results.
Wearing a T-shirt or short-sleeved shirt for the test can make things easier for your child, and you also can bring along a toy or book as a distraction.
Causes Of Low Carbon Dioxide Levels

A number of factors can affect carbon dioxide levels. If your results are outside of the normal range, it may not necessarily mean there is something wrong. However, a normal result also doesnt mean a particular medical condition is absent. Always talk with your doctor to learn more about your test results.
Most of the carbon dioxide in the body is created as a byproduct by cells when they convert sugars and fats into energy. This provides a steady source of CO2, which then leaves the body whenever a person breathes out .
Its very rare for the human metabolism to produce less CO2. Instead, the main reason for low CO2 levels is due to more CO2 leaving the body, usually through increased exhalation .
Several different factors can increase the amount of CO2 that leaves the body. In the following sections, well list out some major reasons for low CO2 levels and the effect that has on ones health.
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How Do I Prepare For A Co2 Blood Test
Before the blood draw, ask your healthcare provider if you should stop taking any medications, vitamins or supplements. Sometimes, certain medications can affect the results of a blood test. Always ask your provider before stopping any medication.
You dont need to stop eating or drinking before a CO2 blood test. But you may be having other blood tests in combination with a CO2 blood test that may require fasting. Ask your healthcare provider in advance if you should fast before the test.
What Happens If Co2 Levels Are Too Low
Too little CO2 in the blood may indicate: Addison’s disease, another disorder of the adrenal glands. In Addison’s disease, the glands don’t produce enough of certain types of hormones, including cortisol. The condition can cause a variety of symptoms, including weakness, dizziness, weight loss, and dehydration.
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Co2 In Blood Low High And Normal Values
Carbon dioxide is a colorless and odorless gas that is considered a waste product of your body. It is carried by your blood to your lungs so that if you breathe out, you release this gas and in exchange, breathe in oxygen. And yes, your body does this process all the time, that is why it is also important to know the normal CO2 levels. Normal CO2 levels in the blood may be indicative of your entire well-being.
Catecholamine Release During Hypercapnia And Exercise
Exposure to environmental hypercapnia frequently results in an elevation of plasma catecholamines. However, it is likely that it is due to an indirect effect of hypercapnia-induced hypoxemia rather than a direct effect of hypercapnia per se. Hypercapnia is usually accompanied by a respiratory acidosis as CO2 is hydrated to form an H+ ion and a HCO 3 â ion . Both CO2 and H+ ions compromise the ability of hemoglobin to bind oxygen and reduce the oxygen-carrying capacity of blood. As such, any elevation of plasma catecholamines during hypercapnia may simply result from CO2 and H+ ions reducing blood oxygen content â a known stimulus for catecholamine release . However, nicotinic receptor-induced catecholamine release can be augmented by an acidic environment around the chromaffin cells or exposure of a fish to hypercapnia.
Benjamin Ko, George Bakris, in, 2018
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Why Do I Need A Co2 In Blood Test
Your health care provider may order a CO2 blood test as part of your regular checkup or if you have symptoms of an electrolyte imbalance. These symptoms may include:
Your provider may also order a CO2 blood test to check for side effects of certain medicines that can cause electrolyte imbalances.
What Does Low Carbon Dioxide In Blood Indicate
Can anxiety cause low CO2 levels in blood?Often one of the first symptoms of a panic attack is hyperventilating , which upsets the natural balance of oxygen and carbon dioxide in our system. One view says a low level of carbon dioxide in the blood directly triggers the symptoms of panic, such as feeling lightheaded and dizzy.
Can dehydration cause low CO2 levels?
A low level may be caused by: Hyperventilation. Aspirin or alcohol overdose. Diarrhea, dehydration, or severe malnutrition.
How do you increase carbon dioxide in your body?
Breathing control via your nose during training. This encourages the body to offload the carbon dioxide and increase the amount of CO2 in the body. The more you do it, you will find that your pace will increase.
What causes low CO2 levels in blood test?
A low CO2 level can be a sign of several conditions, including: Kidney disease. Diabetic ketoacidosis, which happens when your bodys blood acid level goes up because it doesnt have enough insulin to digest sugars. Metabolic acidosis, which means your body makes too much acid.
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Does Anxiety Lower O2 Levels
It works like this: Momentary stress causes the body to tense and you begin to breathe a little more shallowly. A shallow breath lowers oxygen levels in the blood, which the brain senses as stress. Breathing then becomes a little faster and shallower. Oxygen levels fall a little more.
Lower levels of carbon dioxide may mean you have: Metabolic acidosis, or your blood is too acidic. Addison disease, an adrenal gland problem. Ketoacidosis.What do my test results mean?
- Metabolic alkalosis, or too much bicarbonate in your blood.
- Cushing disease.
- Hyperaldosteronism, an adrenal gland problem.
- Kidney failure.
What Is Co2 Blood Test

CO2 blood test is also called bicarbonate blood test, measures the total amount of carbon dioxide in your blood, which occurs mostly in the form of bicarbonate . The CO2 is mainly a by-product of various metabolic processes. Carbon dioxide is an odorless, colorless gas. CO2 is a waste product made by your body. Your blood carries carbon dioxide to your lungs. You breathe out carbon dioxide and breathe in oxygen all day, every day, without thinking about it. A CO2 blood test measures the amount of carbon dioxide in your blood. Changes in your CO2 level may suggest that you are losing or retaining fluid. Too much or too little carbon dioxide in the blood can indicate a health problem. CO2 levels in the blood are affected by kidney and lung function. The kidneys help maintain the normal bicarbonate levels.
Bicarbonate is an electrolyte, a negatively charged ion that is used by the body to help maintain the bodys acid-base balance. It also works with the other electrolytes to maintain electrical neutrality at the cellular level.
Measuring bicarbonate as part of an electrolyte or metabolic panel may help diagnose an electrolyte imbalance or acidosis or alkalosis. Acidosis and alkalosis describe the abnormal conditions that result from an imbalance in the pH of the blood caused by an excess of acid or alkali . This imbalance is typically caused by some underlying condition or disease.
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What Is A Co2 Blood Test
A CO2 blood test measures the amount of carbon dioxide in the blood serum, which is the liquid part of blood. A CO2 test may also be called:
- a carbon dioxide test
- a CO2 test-serum
You may receive a CO2 test as a part of a metabolic panel. A metabolic panel is a group of tests that measure electrolytes and blood gases.
The body contains two major forms of CO2:
Your doctor can use this test to determine if theres an imbalance between the oxygen and carbon dioxide in your blood or a pH imbalance in your blood. These imbalances can be signs of a kidney, respiratory, or metabolic disorder.
Your doctor will order a CO2 blood test based on your symptoms. Signs of an imbalance of oxygen and carbon dioxide or a pH imbalance include:
- shortness of breath
These symptoms may point to lung dysfunction involving the exchange between oxygen and carbon dioxide.
You will need to have your bloods oxygen and carbon dioxide levels measured frequently if youre on oxygen therapy or having certain surgeries.
Blood samples for a CO2 blood test may be taken from either a vein or an artery.
What Causes Metabolic Acidosis
Healthy kidneys have many jobs. One of these jobs is to keep the right balance of acids in the body. The kidneys do this by removing acid from the body through urine. Metabolic acidosis is caused by a build-up of too many acids in the blood. This happens when your kidneys are unable to remove enough acid from your blood.
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How Is The Test Used
The bicarbonate test is usually ordered along with sodium, potassium, and chloride as part of an electrolyte panel, which is included in a basic metabolic panel and a comprehensive metabolic panel . A calculated bicarbonate level might also be reported as part of a blood gas panel.
The electrolyte panel may be used to help detect, evaluate, and monitor electrolyte imbalances and/or acid-base imbalances . The tests may be used as part of a routine health exam or to help evaluate and monitor a variety of chronic or acute illnesses, such as:
- High blood pressure
When acidosis or alkalosis is identified, bicarbonate tests and blood gases may be ordered to evaluate the severity of the pH imbalance. These tests help determine whether it is primarily respiratory or metabolic . They also help monitor treatment until acid-base balance is restored.
Physiological Importance Of Co2 In The Blood
The most important role of carbon dioxide in the blood is to maintain the pH of the blood.
It completes the process of cellular respiration for the generating of energy.
Increases the affinity of oxygen to bind with hemoglobin.
Blood carries carbon dioxide to the lungs and eliminates this waste product. In this way, blood brings oxygen to the cells.
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What Does A Low Carbon Dioxide Level Mean
A low CO2 level can be a sign of several conditions, including: Kidney disease. Diabetic ketoacidosis, which happens when your bodys blood acid level goes up because it doesnt have enough insulin to digest sugars. Metabolic acidosis, which means your body makes too much acid.
How do you treat low CO2 levels?
Maintaining Carbon Dioxide Levels
How do you fix low CO2 levels in blood?
How Is The Water Cycle Negatively Affect The Carbon Cycle
Both are key ingredients to all life on the planet. Interrelationships between the water and carbon cycles. This shows that the water cycle has been altered by the greater amount of carbon in the air. Similarly, plant growth is accelerated by greater carbon levels in the atmosphere.
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What Causes An Abnormal Co2 Result On A Blood Test
It can also detect alkalosis conditions that are metabolic in nature. Certain drugs can increase the bicarbonate levels in the blood and cause an abnormal CO2 blood test result. The most common drugs are loop diuretics and steroids, but certain barbiturates and cortisone combinations can also change results.
Nursing Allied Health And Interprofessional Team Monitoring

While blood gases are a common modality in measuring PCO2, continuous monitoring does exist. Capnography, or the continuous measurement of carbon dioxide, measures the inspired and expired gas in a closed system such as an endotracheal tube. In a healthy adult, the final portion of exhaled gas, labeled end-tidal CO2 , correlated well with PaCO2. There is also the ability to measure transcutaneous carbon dioxide, called PtcCO2. This modality uses a heating element to raise local skin temperature to 42 to 45 degrees C and measures the increased local capillary perfusion with an electrode. Many of these devices also can monitor arterial oxygen saturation in conjunction with a light emitter and sensor similar to a pulse oximeter. While this is also best in healthy adults, it is less accurate in critically ill patients.
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How The Test Works
A doctor or nurse will take a sample of your blood from your arm with a needle. Let your doctor know if you take any medications or supplements, because they can affect the results. So can eating grapefruits, tangerines, and other fruits high in acid.
The test uses only the fluid in your blood, not the blood cells or the platelets that help your blood clot. A lab technician will add acid to the liquid to unlock carbon dioxide from the bicarbonate. The amount of bicarbonate is measured by how fast the sampleâs acidity changes.
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Why And When Do You Need This Test
If you experience signs of an electrolyte imbalance, your healthcare provider may order a CO2 blood test as part of your regular checkup. These are some of the symptoms:
- Breathing difficulties
This is a cash based service and is not covered by insurance at this moment.
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Carbon Dioxide Blood Test Low
The normal range of carbon dioxide in the blood is 23-29 mmol/l. Any levels below this level indicate a low carbon dioxide level. It may indicate an underlying medical condition. However, it should be noted that not all cases of low carbon dioxide levels indicate disease. The level of carbon dioxide may also vary due to other factors such as medications.